HPV Genotyping

HPV genotyping - testing for high-risk types. It detects the presence of human papillomavirus and, when needed, identifies the virus types associated with a higher risk of cervical changes. At Polyclinic Cito the test is performed discreetly, quickly and with a clear explanation of the result - so you know what comes next and when follow-up is truly necessary.

Page Overview

What is HPV typing?

A test that detects the presence of human papillomavirus (HPV) in a sample from the cervix and, if needed, from the vagina. Unlike the Pap test, which assesses cell changes, the HPV test tells whether the virus is present and, depending on the type of test, can identify high-risk types (e.g. types 16/18, which cause around 70% of cervical cancers, and other HR-HPV groups).

Note: HPV infection is common and often clears on its own. According to scientific data from the WHO, up to 80% of sexually active people come into contact with this virus during their lifetime. Most infections clear spontaneously within 1-2 years, but a smaller percentage can lead to changes on the cervix. The key is to recognise the situations when monitoring and follow-up are needed - without unnecessary stress and tests.

What the test may include

  • HPV DNA test - a molecular test that shows the presence of the virus but not its type. 
  • Detection of high-risk types (HR-HPV) - an analysis that shows the presence of high-risk virus groups.
  • Typing/genotyping (as indicated) - a more detailed test that determines the exact type of virus.
  • Interpretation of the findings and recommended follow-up.

When is HPV typing recommended?

This analysis is an important part of modern gynaecological diagnostics, as it allows earlier detection of infections that can lead to changes on the cervix. HPV infection often shows no symptoms, which is why many women are unaware of the presence of the virus. Regular testing detects high-risk types, monitors changes on the cervix and prevents the development of more serious disease. 

Prevention and screening

  • As part of a regular gynaecological examination, according to age and indication
  • As a supplement or alternative to the Pap test (depending on the monitoring plan)
  • If a partner has had an HPV infection or genital warts 
  • Monitoring of a previously confirmed HR-HPV result

Findings and special situations

  • An abnormal Pap result (ASC-US/LSIL, etc.) – as recommended
  • After treatment/changes on the cervix - conisation 
  • For a previously confirmed infection, for monitoring 
  • The need for a clearer assessment of risk and follow-up intervals
A quick decision: If you have a positive HR-HPV result, the aim is to get a clear plan: when the follow-up is, whether colposcopy is needed and what the “next step” is.

What does HPV typing look like?

The procedure is short and similar to taking a Pap test - unhurried and discreet.

1. A short conversation

Before the procedure, the gynaecologist performing the test discusses your medical history, previous findings and the goals of the testing.

2. Taking the sample

As with a gynaecological examination, while the patient lies on the gynaecological chair a swab of the cervix is taken (and of the vagina if needed).

3. Laboratory analysis

In the laboratory, using validated molecular methods, HPV DNA is detected and typing is performed (as indicated). The most common method is PCR, as well as the hybridisation method. 

4. Interpreting the findings

The findings are ready within 2-3 working days, depending on the laboratory and the type of analysis. The gynaecologist explains the findings “in plain language” and any further follow-up and monitoring.

The swab itself is most often only uncomfortable and takes a short time.
We adapt our approach to your sensitivity and situation.

How to prepare for HPV testing?

A few simple rules help to make the findings as reliable as possible.

  • Ideally come outside your period (unless the doctor says otherwise)
  • Avoid sexual intercourse 24-48 h beforehand
  • Avoid vaginal pessaries, creams and douching 24-48 h beforehand

Recommendations before you arrive

  • Previous findings
    If you have older findings that were abnormal, it is advisable to bring them to the examination.
  • Empty your bladder
    It is advisable to empty your bladder before the examination to reduce discomfort.
  • Wear comfortable clothing
    You will need to undress from the waist down, although you can often stay in a skirt (if you are wearing one).
Note:If you have symptoms (itching, burning, discharge) - point this out before the examination.  Sometimes we treat the inflammation first and then carry out the testing, so that the findings are more accurate.

What do you gain from HPV typing?

The aim is less uncertainty and more clarity - what the findings mean and when the next check-up is

1
A clear assessment of the findings
An explanation of the findings (negative, positive for low-risk and positive for high-risk), i.e. whether HPV is present and whether it is a HR-HPV group.
2
A recommendation (with a reason)
What it means in combination with the Pap result and your age.
3
A monitoring plan
When the follow-up is, the direction of further examinations - whether additional work-up is needed (e.g. colposcopy).

In practice this means

  • an explanation of the findings in an understandable way
  • a recommendation for further steps only when they make sense
  • a clear follow-up interval (if needed)
  • less “wandering” between findings and unnecessary tests
Discreet
Clear
Fast

What do you get with HPV typing at Cito Polyclinic?

The difference is in the details: enough time, a calm approach and recommendations that you can understand and follow.

  • An experienced gynaecology team in interpreting the findings 
  • Enough time for questions and conversation 
  • Clear recommendations (what now, what later)
  • A discreet and gentle approach when taking the sample

Want a clear interpretation of your HPV findings?

Send your previous findings (if you have them) and tell us what concerns you - we will suggest the most sensible plan.

Price of HPV typing

The price of taking the sample and processing the HPV swab at Cito Polyclinic is 80€. Additional tests such as a Pap test or  colposcopy are charged separately, as needed. The result is available within two days.

You can get the first available appointment straight away by phone on +385 21 457 800 or by sending a short message via the contact form.

Doctors

Our team of expert physicians

Frequently Asked Questions

Find answers to common questions about this service

What is the difference between low-risk and high-risk HPV types?

Low-risk types are associated with warts and mild changes, while high-risk types (e.g., 16, 18) are linked to precancerous lesions and cervical cancer.

How long until the result is ready and how is the finding interpreted?

The result is usually available within 1-2 days. A positive finding of high-risk types requires monitoring or further workup such as colposcopy.

What if the result is positive - what are the next steps and treatment?

Depending on which Pap test changes accompany a positive HPV finding, further management may include monitoring or additional workup such as colposcopy and biopsy.

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